Image Characteristics of Primary Central Nervous System Lymphomas (PCNSL) and the related pathology <?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

刘树永　耿道颖　冯晓源　何慧瑾

复旦大学附属华山医院放射科 200040

Shu-yong Liu,Dao-ying Geng,Xiao-yuan Feng,Hui-jin He

Department of Radiology, Huashan Hospital attached to Fudan University, 200040

Abstract

Objective：To exploring the CT,MR and MRS characteristics of PCNSL.

Materials and Methods：CT、 MRI and MRS findings in 15 patients with pathologically proved PCNSL were retrospectively analyzed, 9 male and 6 female, Mean age, 57 years old.

Results：On CT scans, the lesions presented as isodensity or slightly hyperdensity masses without calcifications, peritumoral edema was relatively scarce,25％ with obvious edema.The tumor showed markedly homogeneous enhancement after contrast, the lesions displayed hypointensity or isointensity on T₁WI, isointensity or hyperintensity on T₂WI, isointensity or hyperintensity on FLARI, hyperintensity on DWI, which were markedly enhanced in 9 cases, ring-like enhancement in 6 cases,among it 3 cases showing sharp margines,3 cases showing partly defected margines. proton MR spectroscopy showed different spectral peaks including prominent choline-containing compounds, decreased or absence of N-acetyl aspartate，together with a massively elevated lipid resonances. The presence of highly elevated lipids in a solid tumour is more specificity for the diagnosis of PCNSL.

Conclusion：combining the imaging features of PCNSL with the related pathology will be important in diagnosis.

Key words：primary central nervous system lymphomas(PCNSL) Magnetic Resonance Imaging Magnetic Resonance Spectroscopy