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Arterial Infusion Chemotherapy and Embolization of Bronchial Artery in the Treatment Of Lung Cancer

放射科：杨海山 赵 锋 王振常 杨淑琴

内三科：王每先 于运华 李 立 戴绍东

白求恩医科大学第三临床医学院 （长春市 130021）

Yang Hai－Shan et al

3rd Clinical Medical College，Bethune Medical University，Chang chun

Abstract

　　Twenty cases of lung cancer，in Cluding 14 small－Cell carcinomas，4 adenocarcinomas and 2 squamous Cell carcinomas were treated by arterial infusion chemotherapy and embolization of bronchial artery. There were 6 stage Ⅱ and 14 stage III cases in this group. Selective bronchial arteriography showed that all the 20 tumors were surrounded by fairly abundant blood vessels. Infusion was performed via the bronchial artery supplying the tumor with dexamethasone 20mg and adriamycin 40－50mg followed by injection of mitomycin C 20 mg mixed  with iodized oil（40％）1－3ml immediately to embolize the artery.Good results were achieved in all the cases.

　　Key Words：Lung carcinoma  Selective bronchial arteriography（SBAG） Arterial infusion Chemotherapy  Embolization

　　目前，肺癌化疗的总趋势，是尽可能提高肿瘤局部化疗药物的浓度，因此选择性支气管动脉灌注化疗己成为治疗肺癌的有效方法；但如何能使局部药物浓度高并延长作用时间，减少化疗毒性反应，是提高肿瘤局部化疗效果的关键问题。作者自1988年4月至1991年6月对20例肺癌肿瘤血管丰富的病例，采用抗癌药物碘油乳剂进行栓塞治疗；经造影及临床观察随访证实，栓塞完全，药物作用时间长，副作用小，可提高肺癌局部治疗的效果。