Improved left ventricular endocardial border echo resolution by perfluoropropane－albumin microsphere injection：A multiple center stage Ⅲ clinical study<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

王新房　龚培力　谢明星　王朝晖　何亚乐　费洪文　刘媛　崔亮　吴雅峰　徐琳　舒先红　潘翠珍　刘诗珍　智光　吴晓霞　牛海燕　张运　张梅　姚桂华　司延斌　夏小雨

WANG Xin-Fang﹡, GONG Pei-Li, XIE Ming-Xing, WANG Zhao-Hui, HE Ya-Le,

FEI Hong-Wen, LIU Yuan, CUI Liang, WU Ya-Feng, XU Lin, SHU Xian-Hong, PAN Cui-Zhen,

LIU Shi-Zhen, ZHI Guang, WU Xiao-Xia, NIU Hai-Yan, ZHANG Yun, ZHANG Mei,

YAO Gui-Hua, SI Yan-Bin, XIA Xiao-Yu

﹡Union Hospital of Tongji Medical College,

Huazhong University of Science and Technology, Wuhan, 430022 China,

Abstract

Objective：A multiple center research involving 6 hospitals was carried out to evaluate the left ventricular (LV) endocardial border echo enhancement effect and safety of perfluoropropane-albumin microsphere injection.

Methods：Diluted perfluoropropane- albumin microsphere injection was given intravenously to permitted objects at a dose of 0.01ml/kg. Observers A and observers B evaluated the contrast effect respectively by self-comparison between pre-injection and post-injection.