The Neuroprotective Effect of ShenFu Injection（SF） on Patients Undergoing Intra－arterial Thrombolysis（IAT） after Cerebral Stroke<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

刘怀军　贾秀川　刘增品　汪国石　李林芳

河北医科大学第二医院放射科，石家庄 050000

Huai－jun Liu，Zeng－pin Liu，Xiu－chuan Jia，Guo－shi Wang，Lin－fang Li

Department of Radiology，the Second Affiliated Hospital of Hebei Medical University，Shijia zhuang 050000，China

ABSTRACT

Objective：To assess the neuroprotective effect of ShenFu injection（SF） on patients undergoing intra－arterial thrombolysis（IAT） after cerebral stroke.

Methods：45 patients within 6h of acute ischemic stroke onset were treated with IAT.30 patients with complete/partial recanalization were divided into SF treated group and control group randomly.The NIHSS scores before IAT were compared with that after IAT.The NIHSS scores and Modified Rankin Scale（MRS） scores after 3 months were evaluated between two groups.

Results：There are statistic significance in NIHSS scores between two groups after IAT.The Modified Rankin Scale（MRS） scores of SF treated group after 3 months was significantly better than that of control group.

Conclusion：There is definite neuroprotective effect of SF injection in combined use with IAT after cerebral ischemic stroke.Combining thrombolytics with neuroprotective strategies shows great promise and a bright future for cerebrovascular disease.

Key words：intra－arterial thrombolysis（IAT）；reperfusion injury；ShenFu injection；neuroprotective agent