Preliminary Evaluation of ¹ HMR Spectroscopy in Studying Bone and Soft Tissue Diseases of the Lower Limbs<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

周春香　孟悛非　陈应明　罗柏宁　张中伟

Chun－xiang ZHOU, Quan－fei MENG, Ying－ming CHEN,et al .Department of Radiology, No. ¹ Affiliated Hospital, Sun Yat－sen University,Guangzhou,Guangdong Province 510080, P. R. China

Abstract

Objective：To discuss the feasibility and the clinical value of ¹HMR spectroscopy (MRS) in studying bone and soft　tissue diseases of the lower limbs.

Materials and Methods：¹HMRSwas performed to study the lower limbs. The lower limbs of　the subjects had normal skeleton ( n = 10) , normal muscles ( n = 5) , benign lesions ( n = 6) , malignant bone tumor ( n = 11) or　rhabdomyosarcoma ( n = 1) . SVS－STEAM sequence was used.

Results：¹H MRS wave style of the diseased bone and soft－tissue　was different from that of the normal ones , and the difference also existed between benign and malignant lesions. Choline level in　malignant lesions was markedly higher than that in benign lesions.

Conclusion：¹H MRS is an ideal and noninvasive means for the study of biochemical and metabolic characteristics of bone and soft2tissue disorders of the limbs.

Key words：Limb；Bone；Soft－tissue；¹H MRS